Introducing Profunda Health

In Latin and in several Romance languages, profunda means "deep" or "coming from the depths." This term originates from Latin, where "profunda" is the feminine form of "profundus," and it has been preserved with similar meanings across the Romance language family including Spanish, Portuguese and Italian. In all these languages, the word consistently conveys a sense of depth, whether referring to physical depth or metaphorical profoundnes.

That is why today, we're proud to introduce Profunda Health – our first market-ready solution addressing the $14 trillion economic burden of Adverse Childhood Experiences (ACEs) in the United States.

We remain Cepanoa Health – a name that means "to come together" in Nahuatl – honoring our core mission of building community around healing. Profunda represents our new product line that embodies this collective approach while diving deeper into personalized care.

At the core of our approach is a nuanced understanding of childhood adversity and its impacts. Our comprehensive ACEs assessment provides insight into how early experiences affect your current well-being by evaluating different types of adversity before age 18:

• 0: No identified childhood adversity from measured categories

• 1-3: Some exposure to childhood adversity

• 4+: Significant exposure, indicating increased risk for health and social challenges

Unlike platforms that simply calculate an ACEs score and leave you wondering "what now?", Profunda creates accessible healing pathways for everyone. Whether you're just beginning to explore your childhood experiences or seeking intensive support for complex trauma, our tiered approach ensures you receive the right resources at the right time. We've designed Profunda to break down barriers to trauma-informed care – making healing accessible regardless of geography, prior knowledge, or healthcare access.

To further support users, we have included a comprehensive list of resources related to each ACEs question, along with scientific research and articles from medical professionals, health experts, and doctors. These resources offer deeper insights into the effects of childhood adversity and evidence-based strategies for resilience and recovery.

Remember: Your ACE score isn't destiny. Many people with high scores lead fulfilling lives, especially with appropriate support and healing resources. People can still have a lasting impact on

Beyond Surface-Level Wellness

Unlike conventional approaches, Profunda Health targets how childhood trauma embeds itself in our bodies, minds, and relationships. Our comprehensive platform delivers:

• Integrated Care Pathways: Seamlessly connecting social support, education, and clinical care

• Tiered Support: Meeting members at their current stage with appropriate resources

• Precision Health Technology: Creating personalized healing journeys through advanced assessments, including biomarker insights.

The Lasting Impact of Childhood Trauma

The groundbreaking ACEs study by Kaiser Permanente and the CDC revealed how early traumatic experiences correlate with lifelong health and social challenges:

• Chronic health conditions (heart disease, diabetes, autoimmune disorders)

• Mental health challenges (depression, anxiety, PTSD)

• Relationship difficulties and attachment issues

• Emotional regulation problems

• Addictive behaviors

Understanding these connections isn't about blame—it's the first step toward healing.

Your Healing Journey

Healing from childhood trauma requires both courage and support. Our process guides you through:

1. Acknowledging your experiences

2. Understanding connections between past trauma and present challenges

3. Processing difficult emotions in a supportive environment

4. Integrating experiences into your life story with new meaning

5. Growing into new patterns and possibilities

Take the First Step

We invite you to join us on this journey of healing and transformation. Your path to wellness begins here.

Disclaimer: This post is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The ACEs assessment is not a diagnostic tool; while high ACE scores are linked to increased health risks, they do not determine individual outcomes. Profunda Health complements, not replaces, professional healthcare services. If you are in distress or experiencing thoughts of self-harm or harm to others, please seek immediate help—contact your healthcare provider, call 988 (Suicide & Crisis Lifeline), or visit the nearest emergency room

Today, we want to shed light on a critical and often overlooked connection: the relationship between Adverse Childhood Experiences (ACEs) and kidney disease. ACEs are traumatic events that occur before the age of 18, such as:
physical, sexual, or emotional abuse, neglect and/or household dysfunction (divorce, substance abuse, mental illness, incarceration) and community violence.

Many people don't realize that these experiences are not just emotional scars – they have profound physiological consequences that can manifest decades later.

Research has uncovered a startling link between high ACE scores and increased risk of chronic kidney disease (CKD). Here's what we're learning:

Chronic Stress and Physiological Changes: Repeated childhood trauma triggers prolonged stress responses, leading to:
- Elevated cortisol levels
- Chronic inflammation
- Dysregulated immune system
- Altered stress response pathways
- Epigenetic changes affecting kidney cell function
- Increased risk of hypertension and diabetes

We cannot change the past, but we can reshape the future. Recognizing the long shadow of ACEs on kidney health is a critical step toward prevention, early intervention, and more compassionate care. As advocates, healthcare providers, and community members, we have the power to tell our doctors about our ACEs.

Join Cepanoa Health to learn more.

The Intersecting Landscape of Trauma and Immune Health

Women face a unique and complex health challenge at the intersection of psychological trauma and immune system dysfunction. Emerging research reveals a profound connection between Adverse Childhood Experiences (ACEs) and the increased risk of autoimmune diseases, highlighting the critical need for a holistic understanding of women's health.

The Disproportionate Impact

Gender Disparities in Autoimmune Conditions

• Women represent approximately 80% of all autoimmune disease patients

• Conditions like rheumatoid arthritis, lupus, and Hashimoto's thyroiditis predominantly affect women.

• The female-to-male ratio in autoimmune diseases ranges from 3:1 to as high as 9:1 for some conditions

Biological Mechanisms: Stress, Trauma, and Immune Dysregulation

The Hypothalamic-Pituitary-Adrenal (HPA) Axis and Immune Response

Chronic stress from childhood trauma fundamentally alters the body's stress response system:

• Prolonged activation of the HPA axis leads to persistent inflammatory responses

• Cortisol dysregulation can cause immune system hypersensitivity

• Epigenetic changes may reprogram immune cell functioning

Neuroinflammatory Pathways

• Childhood trauma triggers persistent neuroinflammatory processes

• Increases pro-inflammatory cytokine production

• Disrupts neural communication pathways that regulate immune responses

Epidemiological Evidence

A landmark study published in the American Journal of Preventive Medicine demonstrated that:

• Individuals with four or more ACEs have a 70% higher likelihood of developing autoimmune diseases

• Childhood psychological trauma correlates with a 2-3 times increased risk of autoimmune conditions

• Cumulative ACEs show a dose-response relationship with immune system dysfunction

Psychological and Physiological Interconnections

Stress-Induced Immune Modulation

• Chronic psychological stress suppresses natural killer cell activity

• Reduces lymphocyte proliferation

• Increases systemic inflammation markers

Neuroendocrine Disruption

• Traumatic experiences alter hypothalamic-pituitary-adrenal axis functioning

• Impacts cortisol production and inflammatory response regulation

• Creates a persistent state of immune system hypervigilance

Clinical Implications and Whole-Woman Interventions

Recommended Comprehensive Approaches

Trauma-Informed Medical Care

• Screening for ACEs in comprehensive health assessments

• Integrating mental health support with medical treatment

• Developing personalized intervention strategies

Interdisciplinary Treatment Models

• Combining psychological therapies with immunomodulatory treatments

• Stress reduction techniques like mindfulness and cognitive-behavioral therapy

• Nutritional psychiatry focuses on the relationship between diet and mental health, exploring how nutrients impact brain function, mood, and mental disorders. It emphasizes using food and supplements as part of treatment for conditions like depression, anxiety, and cognitive decline.

Future Research Directions

• Investigating precise molecular mechanisms linking childhood trauma to autoimmune diseases

• Developing targeted interventions for early prevention

• Exploring personalized medicine approaches based on individual trauma histories

Conclusion

Understanding the intricate relationship between Adverse Childhood Experiences and autoimmune diseases represents a critical frontier in women's health research. By recognizing the profound mind-body connection, healthcare professionals can develop more nuanced, compassionate, and effective treatment strategies.

Key Takeaway: Childhood trauma is not just a psychological event but a potential biological catalyst with long-lasting immunological consequences.